U-shaped association between triglyceride-glucose index and acute kidney injury in critically ill children with cardiac diseases
The TyG index showed a nonlinear, U-shaped association with AKI in critically ill children with cardiac disease, with inflection points around 8.602 (AKI) and 8.757 (severe AKI). These findings suggest that TyG may support bedside risk stratification in this population.
Authors
- Jiaxiang Du (ORCID: https://orcid.org/0009-0005-3798-284X)
- Jing Song (ORCID: https://orcid.org/0009-0004-8516-4107)
- Xiong Zhang (ORCID: https://orcid.org/0000-0002-5957-7627)
- Sujun Chen
- Ke-Ze Ma
- M D Li (ORCID: https://orcid.org/0009-0000-6887-6568)
- Zhiwei Ye (ORCID: https://orcid.org/0000-0001-7537-2739)
- Fen Zhang (ORCID: https://orcid.org/0000-0002-5384-8019)
- Hao Yu (ORCID: https://orcid.org/0000-0003-2793-7912)
- Weinan Zheng
Institutions
- Dongguan People’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fendo.2025.1598262
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zhejiang University