Predictive factors of body weight loss in patients with type 2 diabetes treated with GLP-1 receptor agonists: a 52-week prospective real-life study
Our results highlight a valuable interplay between body composition, liver involvement, and the incretin response, also suggesting a maximal synergistic effect between metformin and GLP-1RAs when treatments are initiated concurrently rather than sequentially. These data provide valuable insights for the development of individualized treatment strategies.
Authors
- Domenico Triggiani
- Andrea Portacci (ORCID: https://orcid.org/0000-0002-6127-2486)
- Margherita Fanelli (ORCID: https://orcid.org/0000-0002-0128-9745)
- Davide Racaniello
- Sara Volpe (ORCID: https://orcid.org/0000-0002-6831-0457)
- Cosimo Tortorella (ORCID: https://orcid.org/0000-0002-4504-9313)
- Giuseppina Piazzolla (ORCID: https://orcid.org/0000-0003-3221-6562)
- Giuseppe Lisco (ORCID: https://orcid.org/0000-0001-6521-8578)
- Valentina Colaianni
- Antonio Moschetta (ORCID: https://orcid.org/0000-0003-2123-6074)
- Rosselia Maggipinto
- Alfredo Vozza (ORCID: https://orcid.org/0000-0002-0843-8248)
- Carlo Custodero (ORCID: https://orcid.org/0000-0003-1549-6451)
- Valentina Lavarra
- Deborah Coletto
Institutions
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fendo.2025.1674308
- Citations
- 2
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.59