Anti-inflammatory and antioxidant effects of Pogostemon stellatus (Lour.) Kuntze via MAPK, NF-κB, and Nrf2 signaling pathways in LPS-activated RAW 264.7 macrophages
MPSK possesses both anti-inflammatory and antioxidant activities through regulation of NF-κB, MAPK, and Nrf2 pathways, suggesting its potential as a therapeutic agent against inflammation and oxidative stress.
Authors
- Haelim Yoon (ORCID: https://orcid.org/0000-0001-9762-6082)
- Yang Gong (ORCID: https://orcid.org/0000-0002-0864-8368)
- Sayeon Cho (ORCID: https://orcid.org/0000-0002-8950-5704)
- Sang Beom Han (ORCID: https://orcid.org/0000-0002-5464-2151)
- Jihye Seo (ORCID: https://orcid.org/0000-0003-4431-7774)
- Jeong Hyun Kim (ORCID: https://orcid.org/0000-0002-8942-0188)
- Md. Salah Uddin (ORCID: https://orcid.org/0000-0003-1242-5500)
Institutions
- Institute of Botany (AZ)
- Chung-Ang University (KR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fphar.2025.1679919
- Citations
- 3
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 5.25
Funders
- National Research Foundation
- Korea Research Institute of Bioscience and Biotechnology
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea