Brain-derived neurotrophic factor prevents LPS-induced dysregulation of GABAergic interneuron markers in mouse hippocampus
BDNF may protect SST GABAergic interneurons from LPS-induced inflammation, providing novel insights into the molecular mechanisms linking inflammation and GABAergic dysfunction in neuropsychiatric diseases.
Authors
- Mounira Banasr (ORCID: https://orcid.org/0000-0003-4619-4632)
- Thomas D. Prévot (ORCID: https://orcid.org/0000-0002-6774-603X)
- Sara Rezaei
- Etienne Sibille (ORCID: https://orcid.org/0000-0001-5832-6570)
- Érica Leandro Marciano Vieira (ORCID: https://orcid.org/0000-0002-4147-5614)
- Yashika Bansal
Institutions
- Centre for Addiction and Mental Health (CA)
- University of Toronto (CA)
Publication Details
- Journal
- Frontiers in Cellular Neuroscience
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fncel.2025.1675003
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Toronto
- Canadian Institutes of Health Research