Impact of chemotherapy on humoral and cellular immune responses to COVID-19 vaccination in patients with solid tumors

These findings support tailored immune monitoring and vaccination strategies in oncology and identify CD27 downregulation as a novel B-cell dysfunction detected by high-dimensional immunophenotyping.

Authors

Institutions

Publication Details

Journal
Frontiers in Immunology
Published
2025-09-25
DOI
https://doi.org/10.3389/fimmu.2025.1664072
Citations
2
Primary Topic
COVID-19 and healthcare impacts
Type
article
Field-Weighted Citation Impact
2.09
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Impact of chemotherapy on humoral and cellular immune responses to COVID-19 vaccination in patients with solid tumors

Silvia Ghezzi, Silvia Marchese, Giorgio Patelli, Renata Grifantini et al.
2 citations
Frontiers in Immunology
COVID-19 and healthcare impacts
2.09
article

Impact of chemotherapy on humoral and cellular immune responses to COVID-19 vaccination in patients with solid tumors

Silvia Ghezzi, Silvia Marchese, Giorgio Patelli, Renata Grifantini, Francesca Vincenti, Andrea Lombardi, Andrea Sartore‐Bianchi, Salvatore Siena, Alessio Amatu, Sergio Abrignani, Arianna Pani, Lorena Donnici, Andrea Favalli, Mauro Bombaci, Paola Gruarin, Federica Tosi, Daniele Piscazzi, Sara Mariano, Alessandra Bandera, Silvia Principato, Andrea Gobbini, Elisa Pesce
article en
2 citations

Abstract

These findings support tailored immune monitoring and vaccination strategies in oncology and identify CD27 downregulation as a novel B-cell dysfunction detected by high-dimensional immunophenotyping.

Frontiers in ImmunologyVol. 16
University of Milan (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Ospedale Maggiore (IT), Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT), Check Point (Israel) (IL), Istituto Nazionale Genetica Molecolare (IT)
Openalex Percentile: Top 10%
COVID-19 and healthcare impacts
2.09
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.