Stable interindividual differences in modafinil’s effect on vigilance during sleep deprivation
Stable interindividual differences in the effectiveness of modafinil to counteract the sleep deprivation-associated decrease in vigilance exist. Further research should focus on quantifying the extent to which modafinil-induced overconfidence and subjective rebound sleepiness actually constitute potential problems in operational environments (e.g., perhaps using war game simulations).
Authors
- Martine Van Puyvelde (ORCID: https://orcid.org/0000-0002-6595-7597)
- Catherine Drogou (ORCID: https://orcid.org/0000-0002-9208-4437)
- Fabien Sauvet (ORCID: https://orcid.org/0000-0002-4298-2319)
- Jeroen Van Cutsem (ORCID: https://orcid.org/0000-0001-6122-7629)
- Nicholas van den Berg (ORCID: https://orcid.org/0000-0003-1099-2472)
- Frédéric Detaille
- Guido Simonelli (ORCID: https://orcid.org/0000-0002-5400-319X)
- Xavier Neyt (ORCID: https://orcid.org/0000-0002-8992-3877)
- Emilie Dessy (ORCID: https://orcid.org/0000-0003-1891-9632)
- Olivier Maîresse (ORCID: https://orcid.org/0000-0001-8428-1185)
- Nathalie Pattyn (ORCID: https://orcid.org/0000-0002-2690-5479)
- An Van Rompay
Institutions
- Vrije Universiteit Brussel (BE)
- Royal Military Academy (BE)
- Sorbonne Paris Cité (FR)
- Service Public de Wallonie (BE)
- Queen Astrid Military Hospital (BE)
- Association Vinçotte Nuclear (BE)
- Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fphar.2025.1607444
- Primary Topic
- Sleep and Work-Related Fatigue
- Type
- article
- Field-Weighted Citation Impact
- 0.00