TACI and BTK gene analysis in predominantly antibody deficiencies among the primary immunodeficiency disorder patients in Bangladesh
The genetic analysis of the TACI gene in CVID patients revealed no pathogenic variants. The BTK gene displayed heterogeneous mutations, with nonsense mutations being the most prevalent. In this cohort, XLA patients presented three <i>de novo</i> point mutations.
Authors
- Abu Naser Ibne Sattar (ORCID: https://orcid.org/0000-0003-2771-5586)
- Kamrul Laila (ORCID: https://orcid.org/0000-0002-5810-5046)
- Md. Mydul Islam (ORCID: https://orcid.org/0000-0002-0786-9150)
- Avizit Sarker (ORCID: https://orcid.org/0000-0002-8352-1199)
- Chandan Kumar Roy (ORCID: https://orcid.org/0000-0003-1679-9454)
- Nusrat Akhtar Juyee
- Tripty Chakrobortty
- Sharmin Ahmed
- Fahmida Hoque
- Partho Protim Chakrobortty
- Mohammad Imnul Islam
- Ismet Niger
Institutions
- Magna International (Germany) (DE)
- Bangladesh Medical University (BD)
- Comilla Medical College (BD)
- Dinajpur Medical College (BD)
- Dhaka Medical College and Hospital (BD)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fmed.2025.1569810
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00