Reliability Of Sofa (Sequential Organ Failure Assessment) Score For Predicting Morbidity And Mortality In Acute Pancreatitis In A Tertiary Care Center

INTRODUCTION Severe pancreatitis can cause high mortality, and scorings are essential in assessing and managing it. We used serial Sequential Organ Failure Assessment (SOFA)scores in assessing patients with acute severe pancreatitis to predict severity, intensive care unit admission, and mortality. MATERIALS AND METHODS Our study was a prospective, single-institutional review of 150 consecutive acute severe pancreatitis patients admitted to Coimbatore Medical College and Hospital from May 2019 to April 2020. Serial SOFA scores were calculated on admission, on days 2, 7, 14, and 21 of these patients. RESULTS The serial SOFA scores correlated significantly with mortality. Highest SOFA score of 11 and mean SOFA score of more than 8 correlated to mortality of more than 80%. Analyzing the trends in the SOFA score, the mortality rate was around 50% when the score increased, 30% when it remained unchanged, and less than 25 % when it showed a decreasing trend. Mortalitydifferences were better predicted by the first 48 hours SOFA score than in the subsequent 48 hours value. Prolonged hospital stay was associated with late mortality when compared with groups. When comparing other variables, the majority of pancreatitis was caused by alcohol consumption with high mortality observed in patients requiring organ support systems. CONCLUSION Changes in SOFA scores over time predicted the progression of organ failure, and escalating changes in SOFA score on hospital day 1 were subsequently associated with higher mortality rates. In our study, serial assessment of SOFA scores was found to be a cost-effective and easy method for predicting morbidity and mortality in acute pancreatitis patients.