Meta-analysis to Investigate the Correlation Between Event-Free Survival and Overall Survival in Patients with Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma
Strong trial-level correlations were observed between EFS and OS, suggesting EFS is a valid surrogate for OS in patients with resectable LA-HNSCC, particularly in trials investigating neoadjuvant therapy + surgery + adjuvant therapy.
Authors
- Yuexin Tang (ORCID: https://orcid.org/0000-0001-6528-4145)
- Ali Mojebi (ORCID: https://orcid.org/0000-0003-2318-8627)
- Sam Keeping (ORCID: https://orcid.org/0000-0002-4281-1536)
- Braden Hale
- Sanjay Merchant
- Dandan Zheng (ORCID: https://orcid.org/0000-0002-6460-4036)
- Sichen Liu (ORCID: https://orcid.org/0009-0009-4961-359X)
Institutions
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- MD Precision (Canada) (CA)
Publication Details
- Journal
- Advances in Therapy
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1007/s12325-025-03351-z
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85