Effectiveness of therapy with recombinant human growth hormone (rhGH) in patients with hypoplastic left heart syndrome (HLHS) and short stature

Growth failure in patients with HLHS is likely multifactorial in origin, extending beyond the cardiac defect and its treatment. Short stature in this population warrants thorough evaluation, and in cases of confirmed GHD, rhGH therapy should be considered when feasible. Treatment decisions must be individualized, considering the patient's overall clinical condition and coexisting comorbidities.

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Publication Details

Journal
Endokrynologia Polska
Published
2025-09-25
DOI
https://doi.org/10.5603/ep.106211
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
Field-Weighted Citation Impact
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article

Effectiveness of therapy with recombinant human growth hormone (rhGH) in patients with hypoplastic left heart syndrome (HLHS) and short stature

Dorota Roztoczyńska, Anna Wędrychowicz, Jerzy Starzyk, Dominika Januś et al.
Endokrynologia Polska
Growth Hormone and Insulin-like Growth Factors
article

Effectiveness of therapy with recombinant human growth hormone (rhGH) in patients with hypoplastic left heart syndrome (HLHS) and short stature

Dorota Roztoczyńska, Anna Wędrychowicz, Jerzy Starzyk, Dominika Januś, Magdalena Ossowska, Aleksandra Furtak, Karolina Komorkiewicz
article en

Abstract

Growth failure in patients with HLHS is likely multifactorial in origin, extending beyond the cardiac defect and its treatment. Short stature in this population warrants thorough evaluation, and in cases of confirmed GHD, rhGH therapy should be considered when feasible. Treatment decisions must be individualized, considering the patient's overall clinical condition and coexisting comorbidities.

Endokrynologia PolskaVol. 76(5)
Jagiellonian University (PL), Uniwersytecki Szpital Dziecięcy (PL)
Openalex Percentile: Top 64%
Growth Hormone and Insulin-like Growth Factors
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Effectiveness of therapy with recombinant human growth hormone (rhGH) in patients with hypoplastic left heart syndrome (HLHS) and short stature — Dorota Roztoczyńska, Anna Wędrychowicz, et al. · Endokrynologia Polska (2025) | TGRS Research Map | TGRS