The diagnostic utility of miRNA21 in systemic sclerosis
miR-21 was suggested as a robust diagnostic biomarker in SSc with superiority over the traditionally utilized antibodies. Additionally, due to its association with arthritis, it is supposed to play a proinflammatory role in addition to its pronounced profibrotic effects. Interestingly, the profibrotic miR-21 may not reflect the extent of skin fibrosis.
Authors
- Laila Ahmed Rashed (ORCID: https://orcid.org/0000-0002-0362-1385)
- May Mohsen Fawzi
- Gehad Gamal Maghraby (ORCID: https://orcid.org/0000-0001-6013-2038)
- Mohamed Tharwat Hegazy (ORCID: https://orcid.org/0000-0002-2939-5611)
Institutions
- Cairo University (EG)
Publication Details
- Journal
- Reumatismo
- Published
- 2025-09-25
- DOI
- https://doi.org/10.4081/reumatismo.2025.1773
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00