A technical report of downstream cerebrospinal fluid lavage for tranexamic acid intrathecal toxicity
This regimen can be considered for these rare but life-threatening cases of tranexamic acid neurotoxicity in which the risks of hemorrhage and infection is outweighed by the potential benefits of cerebrospinal fluid dilution.
Authors
- Mahesh B. Shenai
- Alexis Cournoyer (ORCID: https://orcid.org/0000-0003-2565-0029)
- Nilesh A. Vyas
- Callum Dewar (ORCID: https://orcid.org/0009-0001-1313-9816)
- Melissa Meister (ORCID: https://orcid.org/0009-0007-7833-9927)
- Mohammed Al-Dulaimi
- Danielle Dang (ORCID: https://orcid.org/0000-0002-5004-1033)
- Dan Dinescu
- Emily Gunnells
Institutions
- Walter Reed National Military Medical Center (US)
- Inova Fairfax Hospital (US)
Publication Details
- Journal
- Clinical Toxicology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1080/15563650.2025.2564886
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00