Prospero-related homeobox protein 1 (Prox1) enhances myelin sheath regeneration in injured sciatic nerve
Prox1 protein level is upregulated in injured sciatic nerve, and Prox1 overexpression promotes the increase of MBP protein level, which positively correlates to myelin regeneration in morphology. This strongly suggests that Prox1 promotes myelin regeneration of injured peripheral nerves.
Authors
- Jun Ren (ORCID: https://orcid.org/0000-0002-0275-0783)
- Fanwei Meng (ORCID: https://orcid.org/0000-0003-2068-2275)
- Linlin Jie
- Xuening Jing
- Xiaoni Kong (ORCID: https://orcid.org/0000-0002-1406-051X)
- Jie Liu (ORCID: https://orcid.org/0000-0002-1215-5814)
- Jun Wu (ORCID: https://orcid.org/0000-0002-0678-3435)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- IBRO Neuroscience Reports
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1016/j.ibneur.2025.09.011
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00