Glucocorticoid receptor polymorphisms and bone mineral density in patients receiving conventional glucocorticoid replacement

our study did not confirm a significant association of NR3C1 polymorphisms with BMD in AD patients receiving long-term GC replacement. Currently recommended GC substitution doses seem less harmful to bone, but prospective analyses in larger cohorts of patients are warranted.

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Publication Details

Journal
Endokrynologia Polska
Published
2025-09-25
DOI
https://doi.org/10.5603/ep.106658
Primary Topic
Adrenal Hormones and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Glucocorticoid receptor polymorphisms and bone mineral density in patients receiving conventional glucocorticoid replacement

Marta Fichna, Marek A. Ruchała, Magdalena Żurawek, Elżbieta Wrotkowska et al.
Endokrynologia Polska
Adrenal Hormones and Disorders
article

Glucocorticoid receptor polymorphisms and bone mineral density in patients receiving conventional glucocorticoid replacement

Marta Fichna, Marek A. Ruchała, Magdalena Żurawek, Elżbieta Wrotkowska, Katarzyna Furman
article en

Abstract

our study did not confirm a significant association of NR3C1 polymorphisms with BMD in AD patients receiving long-term GC replacement. Currently recommended GC substitution doses seem less harmful to bone, but prospective analyses in larger cohorts of patients are warranted.

Endokrynologia PolskaVol. 76(5)
Poznan University of Medical Sciences (PL), Institute of Human Genetics (PL), Polyclinic General Hospital (GR), Polish Academy of Sciences (PL)
Openalex Percentile: Top 64%
Adrenal Hormones and Disorders
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