The Course of Progranulin Levels at Admission and During Early Period of Insulin Treatment in Children with Newly Diagnosed Type 1 Diabetes Mellitus
These findings suggest that elevated PGRN levels in children with newly diagnosed T1DM may reflect either an acute inflammatory response to diabetic ketoacidosis or a persistent alteration in metabolic regulation, or both of these, highlighting the potential role of PGRN as a biomarker in the early course of T1DM.
Authors
- Atilla Çayır (ORCID: https://orcid.org/0000-0001-9776-555X)
- Esra Laloğlu (ORCID: https://orcid.org/0000-0001-5189-3564)
- Esra Dişçi (ORCID: https://orcid.org/0000-0003-3657-3620)
- Kamber Kaşalı (ORCID: https://orcid.org/0000-0002-2851-5263)
- Hüseyin Demirbilek (ORCID: https://orcid.org/0000-0001-6374-5884)
- Şeyhmus Kaya (ORCID: https://orcid.org/0000-0002-8701-6675)
- Serkan Bilge Koca (ORCID: https://orcid.org/0000-0002-9724-2369)
- Alev Lazoğlu Özkaya (ORCID: https://orcid.org/0000-0002-2033-3692)
- Ayse Sena Dönmez
Institutions
- Erzurum Regional Training and Research Hospital (TR)
- Kayseri Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Atatürk University (TR)
- Hacettepe University (TR)
Publication Details
- Journal
- Journal of Clinical Research in Pediatric Endocrinology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.4274/jcrpe.galenos.2025.2025-3-9
- Primary Topic
- Diabetes Management and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00