Do we need a health technology assessment approach for non-inferiority specifically? A comment on: clinical equivalence and non-inferiority within health technology assessment by Taylor et al. (2025)

Taylor and colleagues presented a very informative and comprehensive overview on the current practice of performing non-inferiority analysis in HTA. We would like to point out that HTA of potentially non-inferior technologies should be based on balancing potential advantages against potential deficits exactly as for potentially superior technologies.