Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC‐REFUSAL Study
In this multicenter cohort of consecutive patients with atrial fibrillation submitted to LAAC, OAC refusal appeared as an infrequent indication. In this subgroup, LAAC was confirmed to be feasible and safe. The ischemic outcomes rates at 3 years are promising. Further studies are needed to better understand the potential effects of preferring LAAC over OAC.
Authors
- Alexander Sedaghat (ORCID: https://orcid.org/0000-0001-7015-1056)
- Laurent Roten (ORCID: https://orcid.org/0000-0002-0827-1329)
- Kasper Korsholm (ORCID: https://orcid.org/0000-0003-4724-0880)
- Roberto Galea (ORCID: https://orcid.org/0000-0002-2492-9960)
- Jens Erik Nielsen‐Kudsk (ORCID: https://orcid.org/0000-0002-6473-2900)
- Adel Aminian (ORCID: https://orcid.org/0000-0002-4667-9181)
- Lorenz Räber (ORCID: https://orcid.org/0000-0003-0824-3026)
- Tommaso Bini (ORCID: https://orcid.org/0000-0001-6756-3295)
- Vivian Vij (ORCID: https://orcid.org/0000-0003-3783-2743)
- Konstantina Chalkou (ORCID: https://orcid.org/0000-0001-9718-021X)
- George C.M. Siontis (ORCID: https://orcid.org/0000-0003-2128-9205)
- Juan Perich Krsnik
Institutions
- University of Bern (CH)
- University Hospital Bonn (DE)
- University Hospital of Bern (CH)
- Aarhus University Hospital (DK)
- Grand Charleroi Hospital (BE)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1161/jaha.124.040404
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00