Revealing the diversity of commensal corynebacteria from a single human skin site

This study uncovers the hidden diversity of <i>Corynebacterium</i>, an important yet often overlooked group of bacteria inhabiting human skin. Focusing on the underarm and using advanced sequencing techniques, we identified over 200 complete bacterial genomes. This collection includes species not previously known to reside on the skin, as well as two entirely new species, highlighting how little is currently known about this cutaneous genus. Most of these bacteria were isolated from a single individual, underscoring the vast microbial diversity that can exist within one person. By closely examining the corynebacterial community at a single site, we begin to uncover the complex relationships within a true microbial ecosystem. These findings deepen our understanding of the skin microbiome and provide a valuable resource for future research into how these microbes affect skin health, hygiene, and disease.

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Publication Details

Journal
mSystems
Published
2025-09-25
DOI
https://doi.org/10.1128/msystems.00459-25
Citations
1
Primary Topic
Diphtheria, Corynebacterium, and Tetanus
Type
article
Field-Weighted Citation Impact
1.80
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article

Revealing the diversity of commensal corynebacteria from a single human skin site

Michelle Rudden, Holly N. Wilkinson, Reyme Herman, Sean Meaden et al.
1 citations
mSystems
Diphtheria, Corynebacterium, and Tetanus
1.80
article

Revealing the diversity of commensal corynebacteria from a single human skin site

Michelle Rudden, Holly N. Wilkinson, Reyme Herman, Sean Meaden, Matthew J. Hardman, Barry Murphy, Gavin H. Thomas, Anthony J. Wilkinson, Robert Cornmell
article en
1 citations

Abstract

This study uncovers the hidden diversity of <i>Corynebacterium</i>, an important yet often overlooked group of bacteria inhabiting human skin. Focusing on the underarm and using advanced sequencing techniques, we identified over 200 complete bacterial genomes. This collection includes species not previously known to reside on the skin, as well as two entirely new species, highlighting how little is currently known about this cutaneous genus. Most of these bacteria were isolated from a single individual, underscoring the vast microbial diversity that can exist within one person. By closely examining the corynebacterial community at a single site, we begin to uncover the complex relationships within a true microbial ecosystem. These findings deepen our understanding of the skin microbiome and provide a valuable resource for future research into how these microbes affect skin health, hygiene, and disease.

mSystemsVol. 10(10)
Unilever (United Kingdom) (GB), University of Hull (GB), Biomedical Research Institute (US), University of York (GB), Hull York Medical School (GB)
Openalex Percentile: Top 14%
Diphtheria, Corynebacterium, and Tetanus
1.80
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Revealing the diversity of commensal corynebacteria from a single human skin site — Michelle Rudden, Holly N. Wilkinson, et al. · mSystems (2025) | TGRS Research Map | TGRS