Importance of basic science and research training for the future generation of cardiologists

Advances in the battle against cardiovascular diseases depend upon continuously translating emerging scientific knowledge from preclinical studies and clinical trials into innovative and effective therapeutic strategies. Over the past three decades, molecular and cellular biology have undergone a profound transformation, and large-scale, single-cell, and multi-omics studies have enabled investigations on cardiac disease mechanisms with unprecedented precision. However, these rapid advancements have also contributed to a divergence between the needs and aspirations of basic researchers and those of clinical scientists and practicians, to the detriment of discovery science, precision medicine, and cardiovascular healthcare. The present document highlights the importance of education and training in overcoming the gap between discovery and clinical science, by promoting a common language aimed at designing more translationally relevant and impactful discovery science. To achieve this aim, multidisciplinary efforts will be required to better define learning objectives within training programmes, including education in discovery and clinical sciences, promotion of specific mentorship paths, collaborative research efforts, promotion of equality, diversity, and inclusion, and protection of research time and activity within academic, clinical, and research careers.

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Publication Details

Journal
European Heart Journal
Published
2025-09-25
DOI
https://doi.org/10.1093/eurheartj/ehaf738
Citations
1
Primary Topic
Health and Medical Research Impacts
Type
article
Field-Weighted Citation Impact
1.88

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article

Importance of basic science and research training for the future generation of cardiologists

Ioanna Andreadou, Perry Elliott, Ange Maguy, Sean M. Davidson et al.
1 citations
European Heart Journal
Health and Medical Research Impacts
1.88
article

Importance of basic science and research training for the future generation of cardiologists

Ioanna Andreadou, Perry Elliott, Ange Maguy, Sean M. Davidson, Radosław Parma, Cinzia Perrino, Johann Wojta, Thomas Krieg, Maurizio Pesce, Julien Barc, Sophie Van Linthout, Cecilia M. Linde, Bianca J.J.M. Brundel, Monika M Gladka, T F Luescher, Tomasz J. Guzik, Can Gollmann‐Tepeköylü, Pascal Vranckx, Mélanie Paillard, Carlo G. Tocchetti, Giulio Pompilio, María Rubini Giménez, Petra Kleinbongard, Gemma Chiva‐Blanch, Zoltán Giricz, Katrin Streckfuß‐Bömeke, Elisa A. Liehn, Paul C. Evans, Theresa McDonagh, Matthias Thielmann, Panagiotis Vardas
article en
1 citations

Abstract

Advances in the battle against cardiovascular diseases depend upon continuously translating emerging scientific knowledge from preclinical studies and clinical trials into innovative and effective therapeutic strategies. Over the past three decades, molecular and cellular biology have undergone a profound transformation, and large-scale, single-cell, and multi-omics studies have enabled investigations on cardiac disease mechanisms with unprecedented precision. However, these rapid advancements have also contributed to a divergence between the needs and aspirations of basic researchers and those of clinical scientists and practicians, to the detriment of discovery science, precision medicine, and cardiovascular healthcare. The present document highlights the importance of education and training in overcoming the gap between discovery and clinical science, by promoting a common language aimed at designing more translationally relevant and impactful discovery science. To achieve this aim, multidisciplinary efforts will be required to better define learning objectives within training programmes, including education in discovery and clinical sciences, promotion of specific mentorship paths, collaborative research efforts, promotion of equality, diversity, and inclusion, and protection of research time and activity within academic, clinical, and research careers.

European Heart Journal
Université Claude Bernard Lyon 1 (FR), Semmelweis University (HU), University of Bern (CH), Centre National de la Recherche Scientifique (FR), Karolinska University Hospital (SE), Universitat Oberta de Catalunya (ES), Innsbruck Medical University (AT), Inserm (FR), King's College - North Carolina (US), Medical University of Silesia (PL), Queen Mary University of London (GB), University of Southern Denmark (DK), University of Milan (IT), Universität Innsbruck (AT), Justus-Liebig-Universität Gießen (DE), National and Kapodistrian University of Athens (GR), University of Cambridge (GB), Cardiovascular Institute of the South (US), University of Würzburg (DE), King Faisal Specialist Hospital & Research Centre (SA), Instituto de Salud Carlos III (ES), Centro Cardiologico Monzino (IT), Biomedical Research Foundation of the Academy of Athens (GR), Jessa Hospital (BE), Comprehensive Cancer Center Mainfranken (DE), Molecular Partners (Switzerland) (CH), Deutsches Herzzentrum der Charité (DE), Amsterdam Neuroscience (NL), Federico II University Hospital (IT), Hygeia Hospital (GR), Universitätsklinikum Würzburg (DE), Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition (FR), German Centre for Cardiovascular Research (DE), Spanish National Centre for Cardiovascular Research (ES), University Hospital of Heraklion (GR), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Institut du Thorax (FR), William Harvey Research Institute (GB), Ludwig Boltzmann Institute for Cancer Research (AT), Amsterdam University Medical Centers (NL), King's College Hospital (GB), West German Heart and Vascular Center Essen (DE), Ludwig Boltzmann Institute for Digital Health and Prevention (AT), University College London (GB), University of Turin (IT), University of Duisburg-Essen (DE), Medical University of Vienna (AT), Vrije Universiteit Amsterdam (NL), Hasselt University (BE), University of Amsterdam (NL), University of Edinburgh (GB)
Deutsches Zentrum für Herz-Kreislaufforschung, European Commission, Ministero della Salute, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Lunds Universitet, Odense Universitetshospital, Turun Yliopisto, Universidade de Coimbra, Università di Bologna, Nemzeti Kutatási Fejlesztési és Innovációs Hivatal, Turun Yliopistollinen Keskussairaala, Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición, Innovációs és Technológiai Minisztérium, Lietuvos Sveikatos Mokslų Universitetas, Instituto de Salud Carlos III, European Regional Development Fund, Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, National Research, Development and Innovation Office, Suomen Kardiologinen Seura
Openalex Percentile: Top 12%
Health and Medical Research Impacts
1.88
DOIOpen Access PDFOpenAlex
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