Genotyping HPV 16 and 18 in oral and oropharyngeal cancer: uncovering HIV as a key risk factor in a Ugandan cohort
Overall, HPV 16 and 18 are key etiological factors in oral and oropharyngeal squamous cell carcinoma pathogenesis in the Ugandan population, with a high prevalence. The results suggest that HIV positive individuals are at a higher risk of acquiring HPV 16 associated OPSCC. Alcohol consumption and cigarette smoking are not factors associated with HPV associated OPSCC in this study population.
Authors
- Adriane Kamulegeya (ORCID: https://orcid.org/0000-0002-0703-8920)
- Michael Odida
- Eriab Nkamba
- M. Staudt Louis
- Christopher Kintu (ORCID: https://orcid.org/0000-0002-8243-2354)
- Annah Margret Biira
Institutions
- Gulu University (UG)
- Queen Mary University of London (GB)
- Makerere University (UG)
Publication Details
- Journal
- Infectious Agents and Cancer
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1186/s13027-025-00691-x
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Health, Uganda