Evaluating the impact of trade-offs in diagnostic test accuracy, time-to-isolation, and accessibility on outbreak response for the Ebola virus: a mathematical modeling study

When coupled with a more rapid turnaround time and increase in test access, the use of a lower performance test can result in significantly reduced epidemic size compared to relying on PCR alone in an EBOV outbreak in a resource-limited setting.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-09-25
DOI
https://doi.org/10.1186/s12879-025-11273-y
Citations
1
Primary Topic
Viral Infections and Outbreaks Research
Type
article
Field-Weighted Citation Impact
1.40
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article

Evaluating the impact of trade-offs in diagnostic test accuracy, time-to-isolation, and accessibility on outbreak response for the Ebola virus: a mathematical modeling study

Emmanuel Agogo, Isabella Eckerle, Devy Emperador, Brooke E Nichols et al.
1 citations
BMC Infectious Diseases
Viral Infections and Outbreaks Research
1.40
article

Evaluating the impact of trade-offs in diagnostic test accuracy, time-to-isolation, and accessibility on outbreak response for the Ebola virus: a mathematical modeling study

Emmanuel Agogo, Isabella Eckerle, Devy Emperador, Brooke E Nichols, Nicole A. Boer
article en
1 citations

Abstract

When coupled with a more rapid turnaround time and increase in test access, the use of a lower performance test can result in significantly reduced epidemic size compared to relying on PCR alone in an EBOV outbreak in a resource-limited setting.

BMC Infectious DiseasesVol. 25(1)
University of Geneva (CH), FIND (CH), Hôpital Beau-Séjour (CH), Amsterdam Institute for Global Health and Development (NL), Vrije Universiteit Amsterdam (NL)
Openalex Percentile: Top 16%
Viral Infections and Outbreaks Research
1.40
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