Assessment of Cytokines TNF-alpha, IFN-gamma, TGF-beta-1, and IL-10 in Malaria Patients of the River Nile State , Sudan: A critical study of immune response
The study's findings show how cytokines affect the immune response, impacting both parasite clearance. TNF-α, IFN-γ, and TGF-β1 are positively linked to parasite density (r = 0.42, 0.38, 0.51; P < 0.01). IL-10 levels were higher in P. falciparum compared to P. vivax (560.0 vs. 415.6 pg/mL, P = 0.019).
Authors
- Tibyan Abdalmajed Altaher (ORCID: https://orcid.org/0000-0002-5431-7244)
- Shereen Fahmy
- Ghanem Mohammed Mahjaf (ORCID: https://orcid.org/0000-0002-9615-0964)
- Mosab Nouraldein Mohammed Hamad (ORCID: https://orcid.org/0000-0002-7819-3258)
- Ghadeer Mohsen Albadrani (ORCID: https://orcid.org/0000-0001-5657-4650)
- Rania Saad Suliman
- Sara Ahmadi Badi (ORCID: https://orcid.org/0000-0001-8679-1277)
- Aisha Ali M Ghazwani (ORCID: https://orcid.org/0000-0002-4214-9554)
- Sàdaf Noor (ORCID: https://orcid.org/0000-0002-4153-7547)
- Habab Merghani Yassin (ORCID: https://orcid.org/0000-0003-1975-8973)
- Ammar Abdelmola
- Gehan Ahmed Mohamed Othman
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Damietta University (EG)
- Nile Valley University (SD)
- Omdurman Islamic University (SD)
- University of El Imam El Mahdi (SD)
- Shendi University (SD)
- Prince Sultan Military College of Health Sciences
- King Khalid University (SA)
- Jazan University (SA)
Publication Details
- Journal
- BMC Immunology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1186/s12865-025-00753-0
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- King Khalid University