ANTIADHESIVE EFFECTS OF EXOPOLYSACCHARIDES ISOLATED FROM LIMOSILACTOBACILLUS REUTERI

Probiotics with their biological properties and products contribute to optimal functioning of organ systems and form a natural barrier against the growth of undesirable microorganisms. Exopolysaccharides (EPS) isolated from selected strains of Lactobacilli are tested for their antiadhesive, anti-biofilm and other beneficial effects. EPS isolated from the SL16 strain of Limosilactobacillus reuteri (formerly Lactobacillus reuteri) significantly reduced adhesion of Staphylococcus aureus CCM 3953 and Proteus mirabilis CCM 7188, and this effect was directly proportional to EPS concentration and stronger against S. aureus CCM 3953. Achieved results indicated an anti-biofilm potential of EPS obtained from intestinal Lactobacilli, probably attributable to antiadhesive activity of the tested EPS. Further studies will be required in order to clarify a mechanism of the anti-biofilm effect at the molecular level. Within the research into innovative anti-biofilm agents (biodegradable and non-toxic), the results obtained may facilitate the development of more efficient procedures or preparations that will be used in pharmacotherapy.