Pulmonary calcified nodules and cysts as the initial presentation of Sjögren’s syndrome secondary nodular pulmonary amyloidosis: a rare case report
Pulmonary amyloidosis is a rare pulmonary manifestation of SS, especially with atypical early clinical symptoms, which can render diagnosis challenging. This case highlights that amyloidosis diagnosis precedes SS diagnosis. Moreover, it aims to alert clinicians that when multiple calcified nodules and cystic lesions are observed on chest CT, secondary pulmonary amyloidosis should be considered, and further investigations into related diseases such as SS should be conducted to avoid missed diagnoses.
Authors
- Xiyan Zhu (ORCID: https://orcid.org/0000-0002-1751-4433)
- Zhang Chao-ying
- Zhi Fang (ORCID: https://orcid.org/0000-0002-0724-8485)
- Yingming Jin
Institutions
- Ningbo No. 2 Hospital (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1186/s12890-025-03876-7
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zhejiang Medical Association