Optimization of 99mTc-SPECT in the presence of 90Y for radioembolization
<sup>99m</sup>Tc imaging in the presence of <sup>90</sup>Y leads to substantial image degradation due to crosstalk effects. Monte Carlo-based crosstalk compensation in combination with a ME or HE collimator was identified as the most accurate, robust and visually optimal reconstruction method for <sup>99m</sup>Tc SPECT from dual-isotope data.
Authors
- Camiel E.M. Kerckhaert (ORCID: https://orcid.org/0009-0009-1535-6951)
- Niek Wijnen (ORCID: https://orcid.org/0009-0001-1700-6930)
- Marnix G. E. H. Lam (ORCID: https://orcid.org/0000-0002-4902-9790)
- Maarten L. J. Smits (ORCID: https://orcid.org/0000-0003-4735-655X)
- Hugo W. A. M. de Jong (ORCID: https://orcid.org/0000-0002-3000-8316)
- Martijn M. A. Dietze (ORCID: https://orcid.org/0000-0003-1159-3510)
- Marjolein B.M. Meddens (ORCID: https://orcid.org/0000-0002-9965-1342)
- Rob van Rooij (ORCID: https://orcid.org/0000-0001-8546-8283)
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1186/s40658-025-00798-5
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Federation of Pharmaceutical Industries and Associations
- European Commission
- HORIZON EUROPE Framework Programme