Lymph node ratio predicts adjuvant chemotherapy benefit in esophageal squamous cell carcinoma
These findings suggest that LNR is a valuable marker for identifying ESCC patients who would benefit from postoperative adjuvant chemotherapy. A threshold LNR of 11% can help personalize treatment strategies, and patients with higher LNRs may require more intensive approaches like chemoradiotherapy to improve survival. Further prospective studies are needed to validate these results.
Authors
- Wei Dai (ORCID: https://orcid.org/0000-0003-1650-1590)
- Jun Peng (ORCID: https://orcid.org/0000-0001-5732-4899)
- Xuefeng Leng (ORCID: https://orcid.org/0000-0002-5897-0419)
- Xiang Zhuang
- Yehan Zhou (ORCID: https://orcid.org/0000-0003-2486-6362)
- Na Li (ORCID: https://orcid.org/0009-0001-8624-0114)
- Xiang Wang (ORCID: https://orcid.org/0000-0002-9629-3084)
- Yi Wang (ORCID: https://orcid.org/0000-0002-3262-5254)
- Qifeng Wang (ORCID: https://orcid.org/0000-0001-8544-9007)
- Lei Wu (ORCID: https://orcid.org/0000-0001-9762-0684)
- Haoyue Hu (ORCID: https://orcid.org/0000-0002-9831-5398)
- Lin Peng (ORCID: https://orcid.org/0000-0002-3418-7569)
Institutions
- University of Electronic Science and Technology of China (CN)
- Sun Yat-sen University (CN)
- Suizhou Central Hospital (CN)
- Sichuan Cancer Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- The Oncologist
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1093/oncolo/oyaf315
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology of Sichuan Province