Probing the Cardiovascular Toxic Effects of Long-Term Exposure to Dibutyl Phthalate in Sprague-Dawley Rats Based on Oxidative Inflammation and Metabolic Pathways: Implications for the Heart and Blood Vessel
Long-term exposure to DBP can induce cardiovascular toxicity in rats, manifesting as cardiac and vascular damage, as well as alterations in organ function. This process is characterized by oxidative stress, activation of the pyroptosis pathway, inflammatory responses, and modifications to metabolic pathways.
Authors
- Deyu Zhu (ORCID: https://orcid.org/0000-0002-2949-9410)
- Xiao Liang (ORCID: https://orcid.org/0000-0002-1967-1117)
- Qingling Feng (ORCID: https://orcid.org/0000-0003-1288-300X)
- Qi Huang (ORCID: https://orcid.org/0000-0001-6788-3432)
- Ping Ma (ORCID: https://orcid.org/0009-0003-7246-3143)
- Xu Yang (ORCID: https://orcid.org/0000-0001-8015-6299)
- Yang‐Chang Wu (ORCID: https://orcid.org/0000-0001-7815-2686)
- Cuiyu Bao
- Zehong Wei (ORCID: https://orcid.org/0000-0003-0688-1032)
- Xinyu Bao (ORCID: https://orcid.org/0009-0008-8230-349X)
Institutions
- Beijing Normal University (CN)
- Antioch University (US)
- Hubei University of Science and Technology (CN)
Publication Details
- Journal
- Toxics
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3390/toxics13100815
- Citations
- 2
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 2.64
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- Hubei University
- Hubei University of Science and Technology