Adjacent-differential network with shallow attention for polyp segmentation in colonoscopy images

Colonoscopy is the gold standard for the examination and detection of polyps, with over 90% of polyps potentially progressing into colorectal cancer. Accurate polyp segmentation plays a pivotal role in the early diagnosis and treatment of colorectal cancer. Most existing methods ignore inconsistent colors of colonoscopy images and fuse features of different layers by directly using element-wise addition or concatenation. The former operation may lead to overfitting, while the latter can weaken the complementarity between different levels. In order to resolve these challenges, we propose a deep adjacent-differential network with shallow attention for polyp segmentation (ADSANet). Initially, we develop a color exchange strategy based on uncorrelated and specular region suppression to decouple image content from colors. This strategy allows the model to prioritize the target appearance, reducing the risk of overfitting to color features. To maximize the synergy between layers, we first propose an adjacent-differential feature fusion module (ADFM) and then employ the shallow attention module (SAM) for further feature fusion. Specifically, the ADFM generates differential features between adjacent layers and combines features at the corresponding level in the encoder, as well as the adjacent decoder features. We sequentially apply the ADFM at different scale levels for feature decoding, and the final prediction is computed by fusing the outputs of the sequentially connected ADFMs and the shallow attention module. Extensive experiments on five datasets show ADSANet outperforms most state-of-the-art convolutional neural networks (CNN)-based methods, ADSANet yields significant gains of 18.5%, 3.5%, 3.8%, 4.0%, and 1.7% over classical method PraNet on ETIS, ClinicDB, Endoscene, ColonDB, and Kvasir-SEG respectively, which demonstrates the effectiveness of the proposed scheme of color exchange and adjacent-differential feature fusion for more accurate polyp segmentation.

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Publication Details

Journal
Scientific Reports
Published
2025-09-25
DOI
https://doi.org/10.1038/s41598-025-15470-2
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
Field-Weighted Citation Impact
0.00

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article

Adjacent-differential network with shallow attention for polyp segmentation in colonoscopy images

Wensheng Pan, Liping Zhao, Chao Fu, Hancan Zhu et al.
Scientific Reports
Colorectal Cancer Screening and Detection
article

Adjacent-differential network with shallow attention for polyp segmentation in colonoscopy images

Wensheng Pan, Liping Zhao, Chao Fu, Hancan Zhu, Keli Hu, Chen Wang, Weijun Yang
article en

Abstract

Colonoscopy is the gold standard for the examination and detection of polyps, with over 90% of polyps potentially progressing into colorectal cancer. Accurate polyp segmentation plays a pivotal role in the early diagnosis and treatment of colorectal cancer. Most existing methods ignore inconsistent colors of colonoscopy images and fuse features of different layers by directly using element-wise addition or concatenation. The former operation may lead to overfitting, while the latter can weaken the complementarity between different levels. In order to resolve these challenges, we propose a deep adjacent-differential network with shallow attention for polyp segmentation (ADSANet). Initially, we develop a color exchange strategy based on uncorrelated and specular region suppression to decouple image content from colors. This strategy allows the model to prioritize the target appearance, reducing the risk of overfitting to color features. To maximize the synergy between layers, we first propose an adjacent-differential feature fusion module (ADFM) and then employ the shallow attention module (SAM) for further feature fusion. Specifically, the ADFM generates differential features between adjacent layers and combines features at the corresponding level in the encoder, as well as the adjacent decoder features. We sequentially apply the ADFM at different scale levels for feature decoding, and the final prediction is computed by fusing the outputs of the sequentially connected ADFMs and the shallow attention module. Extensive experiments on five datasets show ADSANet outperforms most state-of-the-art convolutional neural networks (CNN)-based methods, ADSANet yields significant gains of 18.5%, 3.5%, 3.8%, 4.0%, and 1.7% over classical method PraNet on ETIS, ClinicDB, Endoscene, ColonDB, and Kvasir-SEG respectively, which demonstrates the effectiveness of the proposed scheme of color exchange and adjacent-differential feature fusion for more accurate polyp segmentation.

Scientific ReportsVol. 15(1)
Shaoxing University (CN), Peking University (CN), Shaoxing No.6 People's Hospital (CN), Shaoxing People's Hospital (CN), Hangzhou Medical College (CN), Zhejiang University (CN)
National Natural Science Foundation of China, China Postdoctoral Science Foundation, Natural Science Foundation of Zhejiang Province
Openalex Percentile: Top 64%
Colorectal Cancer Screening and Detection
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