Evaluating Web Retrieval–Assisted Large Language Models With and Without Whitelisting for Evidence-Based Neurology: Comparative Study

Restricting retrieval to authoritative neurology domains yielded a clinically meaningful 8 to 18 percentage-point gain in correctness and halved output variability, upgrading a consumer search assistant to a decision-support-level tool that at least performed on par with a specialized literature engine. Lightweight source control is therefore a pragmatic safety lever for maintaining continuously updated, web-based RAG-augmented LLMs fit for evidence-based neurology.

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Publication Details

Journal
Journal of Medical Internet Research
Published
2025-09-25
DOI
https://doi.org/10.2196/79379
Citations
3
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
2.42
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article

Evaluating Web Retrieval–Assisted Large Language Models With and Without Whitelisting for Evidence-Based Neurology: Comparative Study

Sven Guenther Meuth, Lars Masanneck, P. H. Epping, Marc Pawlitzki
3 citations
Journal of Medical Internet Research
Biomedical Text Mining and Ontologies
2.42
article

Evaluating Web Retrieval–Assisted Large Language Models With and Without Whitelisting for Evidence-Based Neurology: Comparative Study

Sven Guenther Meuth, Lars Masanneck, P. H. Epping, Marc Pawlitzki
article en
3 citations

Abstract

Restricting retrieval to authoritative neurology domains yielded a clinically meaningful 8 to 18 percentage-point gain in correctness and halved output variability, upgrading a consumer search assistant to a decision-support-level tool that at least performed on par with a specialized literature engine. Lightweight source control is therefore a pragmatic safety lever for maintaining continuously updated, web-based RAG-augmented LLMs fit for evidence-based neurology.

Journal of Medical Internet ResearchVol. 27
Düsseldorf University Hospital (DE), Heinrich Heine University Düsseldorf (DE)
Openalex Percentile: Top 10%
Biomedical Text Mining and Ontologies
2.42
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