The Resolution of a Biopsy-Proven Enchondroma in the Proximal Humerus Over a 14-Year Interval

Enchondromas are commonly encountered benign cartilaginous tumors that, in most cases, remain stable when followed over time. The loss of cartilaginous matrix is unusual, requiring further investigation into potential regression or malignant degeneration. A few case reports in the literature describe enchondroma regression, but to our knowledge, in the literature in English, only one other case report has shown complete resolution on X-ray. We present an unusual case of complete resolution of a biopsy-proven enchondroma on MRI and bone scan, which contributes to the sparse literature on the natural regression of enchondromas.