Identification and verification of hub biomarkers and immune-related pathways participating in the trabecular meshwork after using corticosteroid
Two key genes (TSC22D3, FKBP5) are involved in the molecular mechanisms in corticosteroids-induce higher IOP. TSC22D3 was probably associated with the immune response in ocular tissue. FKBP5 may be a potential novel diagnostic gene for higher IOP.
Authors
- Yini Sun (ORCID: https://orcid.org/0000-0003-4399-137X)
- Di Song (ORCID: https://orcid.org/0000-0001-6875-5408)
- Xue-feng Pan
- Ziwei Ma (ORCID: https://orcid.org/0000-0001-6362-2198)
- Junhui Zhang (ORCID: https://orcid.org/0000-0003-1406-9220)
- Di Wu (ORCID: https://orcid.org/0000-0002-4753-8161)
- Liwen Wang (ORCID: https://orcid.org/0009-0001-1004-5291)
Institutions
- Huzhou Central Hospital (CN)
- Third People's Hospital of Huzhou (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1371/journal.pone.0331281
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00