Energy-based bond graph models of glucose transport with SLC transporters

In Hunter et al. (2025), we proposed an energy-based modelling framework and presented two exemplar bond graph templates for solute carrier (SLC) transporter families: facilitated diffusion with SLC2A2 (GLUT2) and sodium-glucose cotransport with SLC5A1 (SGLT1). In this article, we provide detailed information on the parameterisation process for these two SLC families and the information required to reproduce the results presented in Hunter et al. (2025).

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Publication Details

Journal
Physiome
Published
2025-09-25
DOI
https://doi.org/10.36903/physiome.30133342
Primary Topic
Protein Structure and Dynamics
Type
article
Field-Weighted Citation Impact
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article

Energy-based bond graph models of glucose transport with SLC transporters

Weiwei Ai, Peter Hunter, David Phillip Nickerson
Physiome
Protein Structure and Dynamics
article

Energy-based bond graph models of glucose transport with SLC transporters

Weiwei Ai, Peter Hunter, David Phillip Nickerson
article en

Abstract

In Hunter et al. (2025), we proposed an energy-based modelling framework and presented two exemplar bond graph templates for solute carrier (SLC) transporter families: facilitated diffusion with SLC2A2 (GLUT2) and sodium-glucose cotransport with SLC5A1 (SGLT1). In this article, we provide detailed information on the parameterisation process for these two SLC families and the information required to reproduce the results presented in Hunter et al. (2025).

Physiome
Openalex Percentile: Top 77%
Protein Structure and Dynamics
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