Blood flow-restricted resistance training modulates miRNAs to improve early hypertensive cardiac function
Eight weeks of blood flow-restricted medium-intensity resistance training could lower SHR blood pressure, and it might also improve early SHR cardiac function by regulating the expression of miR-224-5p, miR-31a-5p, miR-200b-3p, miR-200a-3p, miR-342-3p, miR-429, miR-1949, miR-1249, and miR-350, with the differential expression of miR-200b-3p being particularly significant.
Authors
- Yuchan Zheng (ORCID: https://orcid.org/0000-0002-2991-8478)
- Zhaowen Tan (ORCID: https://orcid.org/0000-0002-2587-1190)
- Jie Zhang (ORCID: https://orcid.org/0009-0002-1324-2116)
- Hao‐Jie Zhu (ORCID: https://orcid.org/0000-0002-2248-4419)
- Yan Zhao (ORCID: https://orcid.org/0000-0001-7555-2991)
Institutions
- Nanjing Normal University (CN)
- Nanjing Sport Institute (CN)
- Nanjing Xiaozhuang University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1371/journal.pone.0333027
- Citations
- 1
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.94