Multimodal analysis investigating the shared pathogenic mechanisms of osteoporosis and osteoarthritis with an initial exploration of the role of ferroptosis
Our findings highlight ferroptosis as a critical pathway in the pathogenesis of both OA and OP. Targeting ferroptosis-related genes and pathways could provide new therapeutic opportunities for managing these musculoskeletal diseases.
Authors
- Chunqing Wang
- Cheng Wei Tony Yang (ORCID: https://orcid.org/0000-0002-1792-1987)
- Weimin Li (ORCID: https://orcid.org/0000-0003-0985-0311)
- Wenyi Li (ORCID: https://orcid.org/0000-0001-9104-4567)
- Di Ran (ORCID: https://orcid.org/0000-0002-6282-8722)
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1371/journal.pone.0332769
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00