Effectiveness and Safety of a Cross-linked Hyaluronic Acid Plus Mannitol Filler for the Correction of Nasolabial Folds in Chinese Subjects: A Randomized, Blinded, Controlled Study

Non-inferiority of the investigational device versus the comparator in correcting NLFs in Chinese subjects was demonstrated. Results up to 12 months suggest comparable safety and effectiveness profiles.

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Publication Details

Journal
Aesthetic Surgery Journal
Published
2025-09-25
DOI
https://doi.org/10.1093/asj/sjaf186
Primary Topic
Facial Rejuvenation and Surgery Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

Effectiveness and Safety of a Cross-linked Hyaluronic Acid Plus Mannitol Filler for the Correction of Nasolabial Folds in Chinese Subjects: A Randomized, Blinded, Controlled Study

Hongyi Zhao, Sheng-Kang Luo, Yan Wu, Benjamin Ascher et al.
Aesthetic Surgery Journal
Facial Rejuvenation and Surgery Techniques
article

Effectiveness and Safety of a Cross-linked Hyaluronic Acid Plus Mannitol Filler for the Correction of Nasolabial Folds in Chinese Subjects: A Randomized, Blinded, Controlled Study

Hongyi Zhao, Sheng-Kang Luo, Yan Wu, Benjamin Ascher, Li Li, Hang Wang, Jinming Zhang, Zhiyong Yang, Hongsen Bi
article en

Abstract

Non-inferiority of the investigational device versus the comparator in correcting NLFs in Chinese subjects was demonstrated. Results up to 12 months suggest comparable safety and effectiveness profiles.

Aesthetic Surgery Journal
Sun Yat-sen University (CN), Jinan University (CN), Peking University (CN), Sichuan University (CN), West China Hospital of Sichuan University (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), Plastic Surgery Hospital (CN), Sun Yat-sen Memorial Hospital (CN), Beijing Hospital (CN), Peking University First Hospital (CN), Air Force General Hospital PLA (CN), Peking University Third Hospital (CN), Guangdong Provincial People's Hospital (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 54%
Facial Rejuvenation and Surgery Techniques
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