Role of weight-adjusted waist circumference index and non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio in prediabetes risk: A mediation analysis
WWI and NHHR were significantly associated with the risk of prediabetes, and NHHR partially mediated the effect of WWI on prediabetes. This study provides a new theoretical basis for early prediabetes screening, prevention, and control. In the future, interventions targeting WWI and NHHR through lifestyle changes may be effective in preventing prediabetes.
Authors
- Cuixiao Wang (ORCID: https://orcid.org/0009-0002-6376-8204)
- Mi Wei (ORCID: https://orcid.org/0000-0002-5761-3970)
Institutions
- Hunan University (CN)
- Changsha University (CN)
- Hunan Mawangdui Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1371/journal.pone.0331866
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00