Role of weight-adjusted waist circumference index and non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio in prediabetes risk: A mediation analysis

WWI and NHHR were significantly associated with the risk of prediabetes, and NHHR partially mediated the effect of WWI on prediabetes. This study provides a new theoretical basis for early prediabetes screening, prevention, and control. In the future, interventions targeting WWI and NHHR through lifestyle changes may be effective in preventing prediabetes.

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Publication Details

Journal
PLoS ONE
Published
2025-09-25
DOI
https://doi.org/10.1371/journal.pone.0331866
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
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article

Role of weight-adjusted waist circumference index and non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio in prediabetes risk: A mediation analysis

Cuixiao Wang, Mi Wei
PLoS ONE
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Role of weight-adjusted waist circumference index and non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio in prediabetes risk: A mediation analysis

Cuixiao Wang, Mi Wei
article en

Abstract

WWI and NHHR were significantly associated with the risk of prediabetes, and NHHR partially mediated the effect of WWI on prediabetes. This study provides a new theoretical basis for early prediabetes screening, prevention, and control. In the future, interventions targeting WWI and NHHR through lifestyle changes may be effective in preventing prediabetes.

PLoS ONEVol. 20(9)
Hunan University (CN), Changsha University (CN), Hunan Mawangdui Hospital (CN)
Openalex Percentile: Top 64%
Diabetes, Cardiovascular Risks, and Lipoproteins
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