Enhancing adverse drug reaction data quality in Canada: A high-precision pipeline for medication name standardization and enrichment
Our transparent and reproducible pipeline effectively resolves medication name heterogeneity in Canada's national ADR database. By transforming variable text into standardized concepts, it significantly enhances data quality, improves the sensitivity of safety signal detection, and facilitates interoperability with global health datasets. The publicly available tool provides a valuable resource for strengthening drug safety surveillance in Canada and beyond.
Authors
- Niaz Chalabianloo (ORCID: https://orcid.org/0000-0001-7228-4725)
- Sheikh Shaugat Abdullah (ORCID: https://orcid.org/0000-0003-2452-8494)
- Kamran Sedig (ORCID: https://orcid.org/0000-0002-6970-5469)
- Flory Tsobo Muanda (ORCID: https://orcid.org/0000-0003-4682-6564)
- Mohammad Ali Omrani (ORCID: https://orcid.org/0000-0001-6847-0699)
- Atefeh Jafari (ORCID: https://orcid.org/0000-0001-5782-3559)
Institutions
- Western University (CA)
- Lawson Health Research Institute (CA)
- London Health Sciences Centre (CA)
- MacEwan University (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1371/journal.pone.0331940
- Citations
- 3
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 3.92