Impact of early PaCO2 and pH fluctuations on neurological outcomes in ARDS patients receiving VV ECMO: a retrospective cohort study from the CSECLS registry
Excessive reductions in PaCO<sub>2</sub> during the early initiation of VV ECMO, rather than pH elevation, were associated with an increased risk of neurological complications in ARDS patients. Close monitoring and management of PaCO<sub>2</sub> during ECMO initiation may mitigate this risk.
Authors
- Xinyi Luo (ORCID: https://orcid.org/0009-0000-9359-5354)
- Zhenting Liang (ORCID: https://orcid.org/0009-0007-0335-4831)
- Xiaotong Hou (ORCID: https://orcid.org/0000-0002-7047-0492)
- Weibo Liang (ORCID: https://orcid.org/0000-0002-8487-3575)
- Ya Wang (ORCID: https://orcid.org/0000-0003-4317-8362)
- Yin Xi (ORCID: https://orcid.org/0000-0001-9743-3010)
- Yonghao Xu (ORCID: https://orcid.org/0000-0002-4905-0979)
- Zhenxing Liang (ORCID: https://orcid.org/0000-0002-8665-3883)
- Chenglong Li (ORCID: https://orcid.org/0000-0002-1773-302X)
- Xiaoqing Liu (ORCID: https://orcid.org/0000-0002-9878-088X)
- Xiaoli Chen (ORCID: https://orcid.org/0000-0001-6835-7768)
- Jie Zhang (ORCID: https://orcid.org/0000-0002-9957-077X)
- Jiao Li (ORCID: https://orcid.org/0000-0002-1996-004X)
- Yimin Li (ORCID: https://orcid.org/0000-0001-8157-6906)
- Jinxiang Ma
- Zhongtao Du
- Weiqun He
- Zhili Zeng (ORCID: https://orcid.org/0000-0001-6794-7862)
- Haixiu Xie
- Jinquan Xie
Institutions
- Capital Medical University (CN)
- Guangzhou Experimental Station (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Beijing Anzhen Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1186/s13613-025-01570-9
- Citations
- 2
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Guangzhou Medical University
- National Natural Science Foundation of China
- Guangdong Medical Research Foundation
- National Science and Technology Major Project