Framework for analyzing MAE-derived immunopeptidomes from cell lines with shared HLA haplotypes

These findings suggest that our approach could be applied to numerous cell lines globally to evaluate a wide array of HLA haplotypes. This may help to reveal candidate vaccine antigens that induce immune protection for a wider population.

Authors

Teesha C. Baker (ORCID: https://orcid.org/0000-0001-7713-4283)
Chia-Wei Kuan
Leonard J. Foster (ORCID: https://orcid.org/0000-0001-8551-4817)
Queenie W. T. Chan
Lina Song (ORCID: https://orcid.org/0009-0008-9987-7617)
H. Yu

Institutions

Agilent Technologies (United States) (US)
University of British Columbia (CA)
University of Kansas Medical Center (US)
Canada's Michael Smith Genome Sciences Centre (CA)
BC Children's Hospital (CA)

Publication Details

Journal: PLoS ONE
Published: 2025-09-25
DOI: https://doi.org/10.1371/journal.pone.0332950
Citations: 1
Primary Topic: vaccines and immunoinformatics approaches
Type: article
Field-Weighted Citation Impact: 0.81

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article

Framework for analyzing MAE-derived immunopeptidomes from cell lines with shared HLA haplotypes

Teesha C. Baker, Chia-Wei Kuan, Leonard J. Foster, Queenie W. T. Chan et al.

Sep 25, 2025

1 citations

PLoS ONE

vaccines and immunoinformatics approaches

0.81

article

Framework for analyzing MAE-derived immunopeptidomes from cell lines with shared HLA haplotypes

Teesha C. Baker, Chia-Wei Kuan, Leonard J. Foster, Queenie W. T. Chan, Lina Song, H. Yu

September 25, 2025article en

1 citations

Abstract

These findings suggest that our approach could be applied to numerous cell lines globally to evaluate a wide array of HLA haplotypes. This may help to reveal candidate vaccine antigens that induce immune protection for a wider population.

PLoS ONEVol. 20(9)

Agilent Technologies (United States) (US), University of British Columbia (CA), University of Kansas Medical Center (US), Canada's Michael Smith Genome Sciences Centre (CA), BC Children's Hospital (CA)

Openalex Percentile: Top 23%

vaccines and immunoinformatics approaches

0.81

DOI Open Access PDF OpenAlex

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Framework for analyzing MAE-derived immunopeptidomes from cell lines with shared HLA haplotypes — Teesha C. Baker, Chia-Wei Kuan, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS