POSSIBLE THERAPEUTIC REPOSITIONING OF VALPROIC ACID: FROM EPILEPTIC SEIZURES TO ACUTE KIDNEY INJURY
Background and Purpose: Acute kidney injury (AKI) is a severe clinical complication with high rates of morbidity and mortality. [Valproic acid](https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?tab=summary&ligandId=7009) is an inhibitor of
Authors
- Danilo S. Alves-Bezerra (ORCID: https://orcid.org/0000-0002-7191-5481)
- Adalberto Vieyra (ORCID: https://orcid.org/0000-0002-8009-7273)
- Isadora Almeida G (ORCID: https://orcid.org/0000-0001-5004-9265)
- Humberto Muzi‐Filho (ORCID: https://orcid.org/0000-0002-9183-1699)
- Glória Costa‐Sarmento
- Amaury Pereira‐Acácio (ORCID: https://orcid.org/0000-0002-5621-7941)
- Luiza Negreiros B
- João Veloso-Santos PM
- Jarlene Lopes A
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade Unigranrio (BR)
- Czech Academy of Sciences, Institute of Biophysics (CZ)
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Published
- 2025-09-25
- DOI
- https://doi.org/10.22541/au.175881254.41643678/v1
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Division of Graduate Education