Immune checkpoint inhibitor-related myocarditis: a comprehensive analysis of clinical manifestations and prognostic factors
Our study identifies multiple key predictors of early mortality in ICI-myocarditis. These results underscore the significance of early detection and vigorous intervention, particularly in patients with extreme troponin elevation or overlapping myositis. Despite higher short-term mortality in high-risk patients, long-term prognosis among survivors appears comparable.
Authors
- Xiaoyan Liu (ORCID: https://orcid.org/0000-0002-1732-5923)
- Shuyang Zhang
- Wei Wu (ORCID: https://orcid.org/0000-0002-9044-0901)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-8293-1321)
- Yan Xu (ORCID: https://orcid.org/0000-0002-9596-2979)
- Yue Fan (ORCID: https://orcid.org/0000-0001-8400-4399)
- Guangcheng Liu (ORCID: https://orcid.org/0009-0004-8138-5930)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- The Oncologist
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1093/oncolo/oyaf285
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- National Science and Technology Major Project