miR-423-5p mediates LINC00886 regulation of ovarian cancer aggressiveness and immune evasion via the TLR4/Myd88/NF-κB/PD-L1 pathway
LINC00886 drives ovarian cancer progression and immune escape through themiR-423-5p/TLR4/Myd88/NF-κB/PD-L1 axis, establishing its potential as both a prognostic biomarker and therapeutic target.
Authors
- Xiaowen Zhang (ORCID: https://orcid.org/0000-0001-5338-1837)
- Chao He
- Zheng Zhang (ORCID: https://orcid.org/0009-0003-2498-9693)
- Na Du (ORCID: https://orcid.org/0000-0001-9540-5876)
Institutions
- Changzhi Medical College (CN)
- Hubei University of Chinese Medicine (CN)
- Yangpu Hospital of Tongji University (CN)
- Qiqihar Medical University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1186/s41065-025-00540-2
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94