Associations of selective serotonin reuptake inhibitors and long COVID risk in patients with depression: a retrospective cohort study
In adult patients with depression, SSRIs compared with non-SSRI antidepressants were associated with a lower risk of long COVID. These results offer preliminary evidence that SSRIs may help prevent long COVID in high‑risk populations and warrant further preclinical and clinical investigation.
Authors
- Zhenxiang Gao (ORCID: https://orcid.org/0000-0002-2223-5092)
- Tomasz Tabernacki (ORCID: https://orcid.org/0000-0003-0650-3349)
- Rong Xu (ORCID: https://orcid.org/0000-0003-3127-4795)
- David C. Kaelber (ORCID: https://orcid.org/0000-0001-7855-9515)
- Pamela B. Davis (ORCID: https://orcid.org/0000-0002-0013-8750)
Institutions
- MetroHealth (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Infection
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1007/s15010-025-02648-z
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00