Cutaneous diphtheria in a child returning from visiting friends & relatives in Burkina Faso: a case report

We present a case report of an 8-year-old African origin, Italian born girl, fully immunized for Diphtheria, with multiple ulcers caused by Corynebacterium diphtheria. The clinical event was preceded by a recent trip to Burkina Faso in a rural area. The atypical presentation with ulcers spread to the entire body and particularly to one leg, led to a bacterial swab, from whose culture the pathogen emerged. The girl was initially empirically treated with amoxicillin/clavulanate and then azithromycin. Cutaneous forms are the most common of all forms and have a relevant spreading role. This case is of particular concern in the context of a rising number of cases in Europe, and it's peculiar since it doesn't regard immigrants and refugees, whereas it regards a fully immunized child who traveled from an endemical country.

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Publication Details

Journal
Infection
Published
2025-09-25
DOI
https://doi.org/10.1007/s15010-025-02636-3
Primary Topic
Diphtheria, Corynebacterium, and Tetanus
Type
article
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article

Cutaneous diphtheria in a child returning from visiting friends & relatives in Burkina Faso: a case report

F Bassani, Laura Vismara, Stefano Rusconi, Bianca Osnaghi et al.
Infection
Diphtheria, Corynebacterium, and Tetanus
article

Cutaneous diphtheria in a child returning from visiting friends & relatives in Burkina Faso: a case report

F Bassani, Laura Vismara, Stefano Rusconi, Bianca Osnaghi, Charles S. Pavia, Roberta Agistri, Luca Pogliani, Gabriele Pagani, Maria Teresa Ticozzelli, S Sciarrabba
article en

Abstract

We present a case report of an 8-year-old African origin, Italian born girl, fully immunized for Diphtheria, with multiple ulcers caused by Corynebacterium diphtheria. The clinical event was preceded by a recent trip to Burkina Faso in a rural area. The atypical presentation with ulcers spread to the entire body and particularly to one leg, led to a bacterial swab, from whose culture the pathogen emerged. The girl was initially empirically treated with amoxicillin/clavulanate and then azithromycin. Cutaneous forms are the most common of all forms and have a relevant spreading role. This case is of particular concern in the context of a rising number of cases in Europe, and it's peculiar since it doesn't regard immigrants and refugees, whereas it regards a fully immunized child who traveled from an endemical country.

InfectionVol. 53(6)
University of Milan (IT), Azienda Ospedaliera Ospedale Civile di Legnano (IT)
Openalex Percentile: Top 77%
Diphtheria, Corynebacterium, and Tetanus
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Cutaneous diphtheria in a child returning from visiting friends & relatives in Burkina Faso: a case report — F Bassani, Laura Vismara, et al. · Infection (2025) | TGRS Research Map | TGRS