The relationship between insomnia and multiple gastrointestinal disorders: a Mendelian randomization study
Through bidirectional MR analysis of nine gastrointestinal disorders, we provide genetic evidence for causal effects of insomnia on four conditions: gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), chronic gastritis, and acute gastritis.
Authors
- Wanying Shen (ORCID: https://orcid.org/0009-0007-6399-8022)
- Bo Chen (ORCID: https://orcid.org/0000-0001-5671-9223)
- Yuanjun Shen (ORCID: https://orcid.org/0000-0002-8183-9531)
- Yu Jin (ORCID: https://orcid.org/0000-0001-6607-4609)
- Yongjin Guo
- Liying Jiang (ORCID: https://orcid.org/0000-0001-5179-2069)
- Zeping Wang
Institutions
- Nantong University (CN)
- Jiading District Central Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai University of Medicine and Health Sciences (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1186/s12876-025-04228-9
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 0.00