Indian Consensus Guidelines for the Management of Pancreatic Cancer
Abstract Pancreatic cancer needs a multidisciplinary approach to treatment. These consensus statements encompass all aspects of treatment of pancreatic cancer within the Indian context. This article outlines consensus-based Indian guidelines for pancreatic cancer (PC), created by a national panel of 39 experts using NCCN and ESMO frameworks. Recommendations were systematically developed via evidence review, expert discussion, and conflict-of-interest exclusions. Guidance covers standardized diagnostic workup, risk stratification and multidisciplinary management involving surgical oncology, medical oncology and radiation oncology. Tumor subtypes (resectable, borderline resectable, locally advanced) determine treatment pathways: upfront surgery for eligible patients and neoadjuvant therapy for downstaging, as appropriate. Preferred regimens for advanced/metastatic disease are outlined. Recommendations are tailored to Indian practice, integrating resource stratification and local access issues. Each guideline is graded for evidence strength and consensus level as per ESMO standards. Emphasis on surveillance and early integrated palliative care aims to optimize patient outcomes. These evidence-based guidelines seek to standardize and elevate PC care across diverse settings in India.
Authors
- Bhawna Sirohi (ORCID: https://orcid.org/0000-0001-8093-1531)
- Shailesh V. Shrikhande (ORCID: https://orcid.org/0000-0002-8036-4212)
- Anant Ramaswamy (ORCID: https://orcid.org/0000-0002-8169-4264)
- Anu R I
- Thomas Seufferlein (ORCID: https://orcid.org/0000-0003-3259-0810)
- Viraj Lavingia (ORCID: https://orcid.org/0000-0003-1981-2693)
- Senthil Jagannathan Rajappa (ORCID: https://orcid.org/0000-0002-5597-756X)
- Fen Saj (ORCID: https://orcid.org/0000-0003-0102-1789)
- Shruti Gohel (ORCID: https://orcid.org/0009-0004-8710-6680)
- Eileen Mary O'Reilly (ORCID: https://orcid.org/0000-0002-8076-9199)
- Tanvi Sood
- Vineet Talwar (ORCID: https://orcid.org/0000-0001-9149-6969)
- Shalini Singh (ORCID: https://orcid.org/0000-0003-3395-9448)
- Sujith Kumar Mullapally
- Munita Menon
Institutions
- All India Institute of Medical Sciences Raipur (IN)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
- University of Malta (MT)
- Pt. Jawahar Lal Nehru Memorial Medical College (IN)
- Tata Memorial Hospital (IN)
- Shalby Hospitals (IN)
- Paras Hospitals (IN)
- Rajiv Gandhi Cancer Institute and Research Centre (IN)
- Basavatarakam Indo American Cancer Hospital and Research Institute (IN)
- Cancer Hospital and Research Institute (IN)
- HCG Cancer Centre (IN)
- Chhattisgarh Council of Science and Technology (IN)
- Apollo Proton Cancer Centre (IN)
- University Hospital Ulm (DE)
Publication Details
- Journal
- Indian Journal of Medical and Paediatric Oncology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1055/s-0045-1811946
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00