Norlanostane triterpenoids from artificially cultivated fruiting bodies of basidiomycete <i>Ganoderma casuarinicola</i>
Two undescribed norlanostane triterpenoids, ganocasuarinones B (<b>1</b>) and C (<b>2</b>), were isolated from the cultivated fruiting bodies of basidiomycete <i>Ganoderma casuarinicola</i>. The structures of the compounds were elucidated by extensive NMR spectroscopic analyses and mass spectrometry data. The absolute configuration of <b>1</b> was established using the modified Mosher method. Ganocasuarinone C (<b>2</b>) exhibited selective cytotoxicity to MCF-7 human breast cancer cells with an IC<sub>50</sub> value of 47 µM.
Authors
- Panida Chinthanom
- Masahiko Isaka (ORCID: https://orcid.org/0000-0002-9229-3394)
- Thitiya Boonpratuang (ORCID: https://orcid.org/0000-0001-6942-2701)
- Seangaroon Yoiprommarat
- Sujinda Sommai (ORCID: https://orcid.org/0000-0003-3672-7271)
- Siriporn Saepua (ORCID: https://orcid.org/0000-0003-1134-4071)
- Kitlada Srichomthong
Institutions
- National Science and Technology Development Agency (TH)
- National Center for Genetic Engineering and Biotechnology (TH)
Publication Details
- Journal
- Journal of Asian Natural Products Research
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1080/10286020.2025.2564414
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00