Randomised trials in child and adolescent health in low- and middle-income countries in 2024–2025

Each year hundreds of randomised controlled trials are conducted in low- and middle-income countries addressing issues in clinical paediatrics and in child and adolescent health. The topics are as diverse as the problems facing children around the world in 2025. This year, 600 trial publications were included in an annual compilation. Many of these studies build on pre-existing evidence and may lead to change in practice or policy. The 600 publications come from all regions of the world.