Effect of gamma knife dose rate and tumor-specific factors on treatment outcomes in brain metastases: insights from a cohort study

This study highlights that dose rate does not significantly impact treatment outcomes in Gamma Knife radiosurgery for brain metastases, indicating that effective tumor control can be achieved even at lower dose rates. These findings provide reassurance regarding the efficacy of treatments utilizing decaying cobalt-60 sources and highlight the importance of patient- and tumor-specific factors in predicting radiosurgical outcomes.

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Publication Details

Journal
Journal of Cancer Research and Clinical Oncology
Published
2025-09-24
DOI
https://doi.org/10.1007/s00432-025-06322-7
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect of gamma knife dose rate and tumor-specific factors on treatment outcomes in brain metastases: insights from a cohort study

Alaattin Fidan, Mustafa Şakar, Beste M. Atasoy, Onur Erdoğan
Journal of Cancer Research and Clinical Oncology
Brain Metastases and Treatment
article

Effect of gamma knife dose rate and tumor-specific factors on treatment outcomes in brain metastases: insights from a cohort study

Alaattin Fidan, Mustafa Şakar, Beste M. Atasoy, Onur Erdoğan
article en

Abstract

This study highlights that dose rate does not significantly impact treatment outcomes in Gamma Knife radiosurgery for brain metastases, indicating that effective tumor control can be achieved even at lower dose rates. These findings provide reassurance regarding the efficacy of treatments utilizing decaying cobalt-60 sources and highlight the importance of patient- and tumor-specific factors in predicting radiosurgical outcomes.

Journal of Cancer Research and Clinical OncologyVol. 151(10)
Marmara University (TR)
Openalex Percentile: Top 63%
Brain Metastases and Treatment
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