Pharmacogenomic Characterization of a Large Cohort of Patient-Derived Cell Lines Identifies Therapeutic Strategies for Pleural Mesothelioma
Pharmacogenomic characterization of a cell line biobank provides a valuable resource on drug sensitivity in mesothelioma and identifies entinostat as a promising therapeutic option, particularly in combination with immune checkpoint inhibitors.
Authors
- Marc‐Antoine Arnould (ORCID: https://orcid.org/0009-0003-2985-8326)
- Esther Stern
- Julie Lasvergnas (ORCID: https://orcid.org/0000-0003-2928-1988)
- Ruth Sequeiros (ORCID: https://orcid.org/0009-0006-8641-8695)
- Françoise Le Pimpec‐Barthes (ORCID: https://orcid.org/0000-0001-6364-4813)
- Christophe Blanquart (ORCID: https://orcid.org/0000-0002-0917-3747)
- Clément Meiller
- Elaine Del Nery (ORCID: https://orcid.org/0000-0002-9654-5202)
- Long Pan (ORCID: https://orcid.org/0000-0003-1550-8280)
- Ori Wald (ORCID: https://orcid.org/0000-0002-8189-0716)
- Sylvie Lantuéjoul (ORCID: https://orcid.org/0000-0003-4310-6975)
- Jessica Zucman‐Rossi (ORCID: https://orcid.org/0000-0002-5687-0334)
- François Montagne (ORCID: https://orcid.org/0000-0001-8182-2695)
- Charles Al Zreibi (ORCID: https://orcid.org/0000-0002-1259-7831)
- Auguste Genovesio (ORCID: https://orcid.org/0000-0003-1877-5595)
- Jean‐Baptiste Assié (ORCID: https://orcid.org/0000-0002-9749-4937)
- Marie‐Claude Jaurand (ORCID: https://orcid.org/0000-0002-0915-6728)
- Didier Jean (ORCID: https://orcid.org/0000-0001-5823-7404)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Hebrew University of Jerusalem (IL)
- Université Paris-Est Créteil (FR)
- Université Paris Cité (FR)
- Université Paris Sciences et Lettres (FR)
- Hadassah Medical Center (IL)
- Sorbonne Université (FR)
- Sorbonne Paris Cité (FR)
- Centre de Recherche des Cordeliers (FR)
- Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Centre Léon Bérard (FR)
- Hôpital Européen (FR)
- Centre de Recherche en Cancérologie de Lyon (FR)
- Institut de Biologie de l'École Normale Supérieure (FR)
- Centre Hospitalier de Valenciennes (FR)
- Hôpital Intercommunal de Créteil (FR)
- Institut Curie (FR)
- Université Grenoble Alpes (FR)
- Nantes Université (FR)
Publication Details
- Journal
- Cancer Research
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1158/0008-5472.can-24-3822
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00